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Good Management Practice (GMP): The 5Ps.

pharmaceutical manufacturing

What is Good Management Practice (GMP)?

Good Management Practice (GMP) is basically a very strict system that ensures pharmaceutical, food and cosmetic products are consistently produced and maintained according to set quality standards.

 Its main objective is to minimise the risk such as adulteration, cross-contamination and mislabelling associated with the manufacturing, processing and packaging of products, so that the consumer as well as the marketplace is not exposed to anything harmful or life threatening.

5Ps of GMP

Now, GMP ensures that the quality of the product is managed by emphasizing on the five key elements, popularly known as 5Ps of GMP- People, Premises, Processes, Products and Procedures.

Once all of the five Ps are followed properly, there is a sixth P…. and that is Profit! Let’s take a brief look below:

1) People

First of all, the people engaged in manufacturing industries should be properly trained. Their responsibilities should be made clear. Employees’ performance should be assessed regularly and they must know how to follow the procedures.

The GMP of a manufacturing company must be strictly adhered to. As such, it is also the manufacturer’s responsibility to repeatedly review the production process so that the training of the employees can be enhanced.

2) Procedures

GMP requires the manufacturer of a manufacturing company to document and record each and every process. All procedures involved must be laid bare and followed to them. In case there is any deviation from the procedure, it must be thoroughly investigated and reported.

If there is any problem with a batch, then it can easily be detected as all the procedures have been documented.

3) Products

Products refer to the final products sold as well as the raw materials involved in the manufacturing of the products. Specifications for raw materials, components, intermediate and finished goods must be made clear at every stage of manufacture.

Standard methods must also be followed for packing, testing and sampling of the products.

4) Premises and equipment

GMP requires for the equipment used in the manufacturing facilities to be continuously validated and assessed.

The manufacturing companies must clearly give record of the cleaning procedures and the conditions of the equipment and the premises.

It also requires for the regulations of the surrounding area, water and waste disposal system to be followed.

5) Processes

Another principle that GMP implements is continuous improvement. This applies to processes as well as the other Ps.  Processes are required to be defined, evaluated and documented.

The manufacturer must be clear with all the processes and should also be available for self-inspection to facilitate further potential improvements. Compliance must be made provable to an audit.

Once all the five Ps are followed successfully, then comes a sixth P and that is Profit.

GMP ensures that a manufacturing company shows compliance with regulations and ensures that the products are fit for use. As such, it brings the company to the image of one which is not shady and follows proper legal instructions. The ability of your company to follows the GMP principles will further contribute to your company’s growth and success

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